Pseudohypoparathyroidism: A Variation on the Theme of Hypoparathyroidism

نویسندگان

  • Amanda Tencza
  • Michael A. Levine
چکیده

Pseudohypoparathyroidism is characterized by an inability of the body to respond appropriately to parathyroid hormone (PTH), the principal hormone that regulates calcium and phosphorous levels in the body. PTH is made by the parathyroid glands in the neck. There are usually four parathyroid glands, but we probably only need one or two of the glands. PTH is missing, or too low, in patients with hypoparathyroidism. Therefore, the fundamental difference between hypoparathyroidism and pseudohypoparathyroidism is that PTH is absent in hypoparathyroidism, but the body will respond to it; and PTH is plentiful in pseudohypoparathyroidism, but the body cannot respond to it!

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تاریخ انتشار 2008